Laurence Zitvogel Selected Research

Interleukins

1/2020	Trial watch: TLR3 agonists in cancer therapy.
1/2018	Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy.
11/2014	Cytokines reinstate NK cell-mediated cancer immunosurveillance.
1/2014	Mature cytotoxic CD56(bright)/CD16(+) natural killer cells can infiltrate lymph nodes adjacent to metastatic melanoma.
1/2014	Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering.
2/2013	Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR+ NK cell levels correlate with disease outcome.
6/2012	Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells.
3/2012	Inflammasomes in carcinogenesis and anticancer immune responses.
3/2011	Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
3/2010	Pyroptosis - a cell death modality of its kind?

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Laurence Zitvogel Research Topics

Disease

319	Neoplasms (Cancer) 07/2022 - 07/2002
44	Melanoma (Melanoma, Malignant) 01/2022 - 07/2002
25	Breast Neoplasms (Breast Cancer) 01/2020 - 09/2007
17	Neoplasm Metastasis (Metastasis) 01/2021 - 03/2004
12	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 05/2012
11	Carcinogenesis 01/2022 - 03/2012
9	COVID-19 01/2022 - 01/2020
9	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 05/2012
9	Carcinoma (Carcinomatosis) 01/2018 - 09/2012
9	Necrosis 01/2017 - 04/2009
8	Inflammation (Inflammations) 01/2022 - 05/2004
8	Lung Neoplasms (Lung Cancer) 01/2020 - 08/2012
7	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2017 - 08/2004
7	Residual Neoplasm 01/2014 - 10/2002
5	Infections 01/2022 - 10/2005
4	Disease Progression 01/2020 - 05/2012
3	Dysbiosis 01/2022 - 01/2016
3	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 10/2012
3	Colonic Neoplasms (Colon Cancer) 01/2021 - 11/2008
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 06/2015
3	Cadaver (Cadavers) 01/2019 - 06/2010

Drug/Important Bio-Agent (IBA)

47	AntigensIBA 01/2022 - 07/2002
37	AnthracyclinesIBA 01/2021 - 03/2007
29	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 12/2007
28	CytokinesIBA 01/2022 - 05/2004
28	VaccinesIBA 01/2022 - 02/2006
24	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2016
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2004
21	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2022 - 06/2006
21	CalreticulinIBA 12/2021 - 01/2007
19	Peptides (Polypeptides)IBA 01/2022 - 09/2003
19	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2007
18	LigandsIBA 01/2021 - 12/2006
16	InterferonsIBA 10/2021 - 02/2006
16	Pharmaceutical PreparationsIBA 07/2020 - 02/2010
16	HMGB1 Protein (HMG1)IBA 06/2016 - 09/2007
15	Monoclonal AntibodiesIBA 10/2019 - 08/2008
14	Adenosine Triphosphate (ATP)IBA 01/2019 - 10/2009
13	Biological ProductsIBA 10/2021 - 01/2003
13	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 03/2006
11	Therapeutic UsesIBA 10/2020 - 12/2007
11	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 06/2006
10	InterleukinsIBA 01/2020 - 03/2010
10	Imatinib Mesylate (Gleevec)FDA Link 01/2017 - 08/2004
9	AntibodiesIBA 12/2021 - 03/2004
9	Anti-Bacterial Agents (Antibiotics)IBA 10/2021 - 11/2013
9	Toll-Like Receptor AgonistsIBA 01/2018 - 10/2008
8	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 06/2006
8	CarcinogensIBA 01/2021 - 07/2011
8	Toll-Like Receptor 4IBA 02/2016 - 09/2007
8	Neoplasm Antigens (Tumor Antigens)IBA 04/2013 - 02/2006
7	Pattern Recognition ReceptorsIBA 01/2021 - 08/2009
7	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020 - 09/2008
7	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2019 - 03/2013
6	Interleukin-2 (IL2)IBA 01/2020 - 10/2002
6	ChemokinesIBA 01/2018 - 06/2008
6	Protein Isoforms (Isoforms)IBA 01/2016 - 08/2004
5	Hormones (Hormone)IBA 01/2022 - 10/2012
5	Immunologic Adjuvants (Immunologic Adjuvant)IBA 02/2016 - 09/2007
5	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2014 - 12/2005
5	Cytotoxins (Cytolysins)IBA 01/2014 - 12/2006
5	Interferon-gamma (Interferon, gamma)IBA 02/2010 - 12/2006
4	Tyrosine Kinase InhibitorsIBA 07/2022 - 06/2011
4	EpitopesIBA 01/2022 - 03/2005
4	Histocompatibility Antigens Class IIBA 01/2019 - 04/2013
4	Chemokine ReceptorsIBA 01/2018 - 09/2015
4	Immunomodulating AgentsIBA 11/2016 - 07/2012
4	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2016 - 03/2011
4	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 06/2016 - 01/2015
4	EnzymesIBA 05/2015 - 12/2011
4	IpilimumabIBA 02/2015 - 11/2012
4	Interleukin-18 (Interleukin 18)IBA 11/2014 - 08/2011
4	Cancer VaccinesIBA 01/2014 - 02/2006
4	Imiquimod (Aldara)FDA LinkGeneric 01/2014 - 08/2012
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2013 - 05/2004
4	HLA-A2 Antigen (HLA A2 Antigen)IBA 03/2005 - 09/2003
3	Immunologic Factors (Immunomodulators)IBA 07/2022 - 01/2016
3	Blocking AntibodiesIBA 01/2022 - 09/2013
3	Antiviral Agents (Antivirals)IBA 01/2022 - 01/2019
3	Immunoglobulin G (IgG)IBA 12/2021 - 12/2012
3	RNA (Ribonucleic Acid)IBA 12/2021 - 01/2020
3	Annexin A1IBA 01/2021 - 01/2019
3	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2021 - 11/2015
3	SpermidineIBA 01/2021 - 11/2016
3	Poly A-UIBA 01/2020 - 01/2010
3	CrizotinibIBA 01/2020 - 01/2019
3	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2020 - 03/2011
3	Interferon Type IIBA 01/2020 - 11/2014
3	Messenger RNA (mRNA)IBA 01/2018 - 01/2017
3	Natural Cytotoxicity Triggering Receptor 1IBA 01/2018 - 01/2015
3	VemurafenibIBA 01/2017 - 01/2014
3	Natural Killer Cell ReceptorsIBA 01/2017 - 06/2011

Therapy/Procedure

123	Therapeutics 07/2022 - 03/2005
84	Immunotherapy 07/2022 - 08/2002
73	Drug Therapy (Chemotherapy) 01/2022 - 12/2005
21	Radiotherapy 01/2020 - 12/2006
6	Adjuvant Chemotherapy 06/2016 - 05/2012
5	Neoadjuvant Therapy 01/2020 - 01/2014
4	Oncolytic Virotherapy 01/2017 - 06/2013
3	Transplantation 10/2021 - 08/2011